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Price: 28.10 USD
Availability: InStock
Rating: 4.6687 (12 reviews)

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Control of p53 and NF-B signaling by WIP1 and MIF: role in cellular senescence and organismal aging

Further studies documented that NTBC was a potent inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPD), which catalyzes conversion of 4-hydroxyphenylpyruvate to homogentisic acid 53 (Figure 1)

2010;6(4), e1000894

Second, being a potent antioxidant, NAC may exert direct effects on some reactive oxygen species (ROS), whereas it is a precursor of cysteine (an essential substrate for glutathione synthesis) and also regulates the redox state by maintaining the thiol pool [20]

Current Western medical treatment is based on disease-modifying anti-rheumatic drugs (DMARDs) (4), but there are problems such as insufficient efficacy, drug resistance and adverse reactions, and the clinical outcomes of RA patients are not satisfactory (3)